This question paper describes the content of the curricula, and provides data to evaluate the implementation, process and immediate post-test knowledge of Project Towards No Tobacco Use (Project TNT). Four different school-based tobacco use prevention curricula have been developed to counteract the effects of three types of tobacco use acquisition variables typically addressed within a comprehensive social influence program: (1) peer approval for tobacco use (normative social influence), (2) incorrect social information provided about tobacco use (information social influence) and (3) lack of knowledge or misperceptions about physical consequences due to tobacco use. Three curricula are designed to counteract the effects of single acquisition variables, while a fourth curriculum is designed to counteract the effects of combined social and physical impact-related influences. These curricula have been delivered by trained project health educators to seventh-grade students to maximize implementation. ‘Program’ schools, those schools that have received one of these curricula, have been compared to ‘control’ schools that provide systematic health education through school staff. A total of five conditions were contrasted using a randomized experiment involving 48 junior high schools in Southern California. This paper documents high levels of implementation in all program conditions. Favorable process ratings were also obtained across the four program conditions, using multiple metrics and sources of ratings (students, health educators, and classroom teachers who observed curriculum delivery). Finally, knowledge item sets completed by the students showed discriminatory validity across all five conditions. Because the program conditions were discriminatory, yet were fairly similar in implementation and process ratings, planned future study of behavioral outcomes can be interpreted as relatively unaffected by delivery or credibility confusion.